long-termdepression相关论文
αCaMKII overexpression impairs behavioral flexibility and NMDAR-dependent LTD in the medial prefront
Objective The medial prefrontal cortex(mPFC)participates in the behavioral flexibility.As a major downstream molecule in......
Objective Calcium/calmodulin-dependent protein kinase Ⅱ(CaMKⅡ)plays an important role in synaptic plasticity,learning ......
ASIC1a regulates insular long-term depression and is required for extinction of conditioned taste av
The synaptic function of acid-sensing ion channel 1a(ASIC1a)is emerging to be understood.Here,we identify a crucial role......
Soluble amyloid β-enhanced LTD in rat dentate gyrus of hippocampus is mGluR1/5-dependent and involve
Accumulation of amyloid beta (Aβ) protein is a key pathogenic element of Alzheimers disease.It is reported that the Aβ......
Neurotoxins are harmful to brain functions,especially interrupting memory processing.Hippocampal synaptic plasticity is ......
The exact roles of acid-sensing ion channels(ASICs)in synaptic plasticity remain elusive.Here,we address the contributio......
Roles of acid-sensing ion channel 1a in synaptic plasticity in the hippocampus:Revisited by multi-el
Acid-sensing ion channels(ASICs)are proton-gated cation channels involved in a variety of physiological and pathological......
In the cerebellum,long-term depression(LTD)of synaptic transmission from parallel fiber(PF)to Purkinje cell(PC)has been ......
Objective Numb is first identified as a cell fate determinant in drosophila and is essential for maintaining neural stem......
Acid-sensing ion channel 1a(ASIC1a)is enriched in insular cortex,a region known for gustatory recognition memory.As ......
目的探讨在体诱导大鼠海马CA1区长时程压抑(LTD)的诱导条件以及淀粉样β蛋白(Aβ)对其影响。方法给予大鼠海马CA1区Schaffer侧枝测......
Cognitive impairment after traumatic brain injury is associated with reduced long-term depression of
Traumatic brain injury can cause loss of neuronal tissue, remote symptomatic epilepsy, and cognitive deficits. However, ......
目的探讨神经病理性疼痛老年大鼠海马CA1区突触长时程抑制（LTD）的变化．方法老年雄性Wistar大鼠15只，随机均分为3组（n=5）：假手术组（S组）、神......
